657 IL-17A upregulates endothelin-1 in keratinocytes in the pathogenesis of Prurigo nodularis
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چکیده
منابع مشابه
The pathogenesis of Prurigo nodularis--'Super-Itch' in exploration.
Prurigo nodularis (PN) is characterized by multiple hyperkeratotic nodules, papules and the presence of intensive pruritus. This leads to an impaired quality of life and high burden due not only to the severe itch but also the chronic, skin lesions and lack of treatment options. The pathogenesis of PN is not completely clarified. Previous studies have demonstrated just how important the interac...
متن کاملPrurigo nodularis: a review.
Prurigo nodularis is a chronic condition characterized by a papulonodular pruriginous eruption of unknown aetiology. This condition is a difficult disease to treat and causes frustration to both the patient and the treating doctor. A variety of systemic conditions have been reported to be associated with prurigo nodularis. The mechanism by which these disorders may trigger prurigo nodularis is ...
متن کاملPrurigo nodularis after acupuncture
CASE A 52-year-old man without a history of atopy was referred to the dermatology clinic at the City of Hope Medical Center for lesions on his arms and legs that had been present for several months. He stated that they began to appear days after receiving traditional needle acupuncture therapy. The location of the lesions on his extremities coincided with where the acupuncture needles had been ...
متن کاملPrurigo nodularis: Picking the right treatment.
Most patients with localized nodules should receive topical treatment first. But disappointing results or specific findings described here could necessitate additional or alternative options.
متن کاملEfficacy of thalidomide in the treatment of prurigo nodularis.
© 2011 The Authors. doi: 10.2340/00015555-0997 Journal Compilation © 2011 Acta Dermato-Venereologica. ISSN 0001-5555 Prurigo nodularis (PN) is a chronic and intensely pruritic dermatosis characterized by lichenified and excoriated papules and nodules. Although thalidomide has shown promise in the treatment of refractory PN, its safety and efficacy for this indication has not been firmly establi...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.733